Kocher–Debre–Semelaigne syndrome
MUSCULAR PSEUDOHYPERTROPHY - HYPOTHYROIDISM, ALSO KNOWN AS KOCHER-DEBRE-SEMELAIGNE SYNDROME IS A RARE DISORDER CHARACTERIZED BY PSEUDOHYPERTROPHY OF MUSCLES DUE TO LONGSTANDING HYPOTHYROIDISM (SEE THIS TERM)
Kocher-Debré-Semélaigne syndrome; Kocher-Debre-Semelaigne syndrome
Kocher–Debré–Semelaigne syndrome is hypothyroidism in infancy or childhood characterised by lower extremity or generalized muscular hypertrophy, myxoedema, short stature and cognitive impairment. The absence of painful spasms and pseudomyotonia differentiates this syndrome from its adult form, which is Hoffmann syndrome.